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The peptide induced expression of cytoskeleton proteins, intracellular kinases, and transcription regulators while repressing immune and inflammatory mediators, leading to down-regulation of oxidative stress response and up-regulation of ion channels and metabolic pathways

Proteomics workflows: affinity and mass spectrometry Presented at the HUPO World Congress, Stuart Cordwell, PhD, University of Sydney, examines how mass spectrometry and affinity proteomics complement one another to advance clinical proteomics

doi: 10.1146/annurev.en.36.010191.001225 38 AshfaqMSonodaSTsumukiH

Jin L, Tabe Y, Konoplev S, Xu Y, Leysath CE, Lu H, Kimura S, Ohsaka A, Rios MB, Calvert L, Kantarjian H, Andreeff M , Konopleva M

In each of these processes there exist potential sites of pharmacogenetics variability (Figure 1)